Table 1

Standard 2 × 2 table used for calculating sensitivity and specificity

Gold standard test resultNew test result positiveNew test result negative
DiseasedTrue positive (TP)False negative (FN)
Non-diseasedFalse positive (FP)True negative (TN)
  • Sensitivity = TP/TP + FN.

  • Specificity = TN/TN + FP.

  • Positive predictive value = TP/TP + FP.

  • Negative predictive value = TN/TN + FN.

  • Likelihood ratio = sensitivity/1 − specificity = TP/(TP + FN)/1 − (TP/(TP + FP).