Table 2

Effect of 17β-oestradiol on fibrinolytic activity and tissue plasminogen activator antigen (t-PA) after nine weeks of treatment

Placebo (mean (SEM))17β-oestradiol
1 mg 2 mg
% change from placebo value (95% CI)
Fibrinolytic activity (mm2)54 (5)+13 (−13 to +42)+48 (+13 to +87)2-150
(p = 0.332)(p = 0.002)
t-PA (ng/ml)8.3 (1.2)−18 (−1 to −31)−31 (−17 to −41)
(p = 0.043)(p < 0.001)
  • 2-150 p < 0.05 v percentage change for 1 mg 17β-oestradiol.