Table 2

Prevalence of seropositivity for antibodies to some chronic infective agents

Seropositive2-150Seronegative2-150Odds ratio and 95% confidence interval
Agent Cases Controls Cases Controls Adjusted for age and sex only Adjusted for age, sex, and other factors 2-151
H pylori 1342941123481.41 (1.05 to 1.90)1.28 (0.93 to 1.75)
C pneumoniae 94234912361.04 (0.74 to 1.48)0.95 (0.66 to 1.36)
Cytomegalovirus114221822451.57 (1.11 to 2.22)1.40 (0.96 to 2.05)
  • 2-150 For C pneumoniae and cytomegalovirus antibodies, analysis by thirds of titres was prespecified—that is, seropositive samples were defined as those in the top third of the distribution, and seronegative samples as those in the bottom third, whereas manufacturer’s recommended cut off was used to determine H pylori sensitivity.

  • 2-151 Cigarette smoking (current, ex, never; number of cigarettes/day), markers of socioeconomic status (age at stopping education; occupation; housing tenure; car ownership; marital status; employment status), non-fasting serum total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglycerides, resting systolic and diastolic blood pressures, body mass index, and previous history of diabetes.