Contribution of individual treatments to the fall in coronary heart disease mortality in Scotland, 1975 to 1994. Deaths prevented or postponed as a result of treatments
| Treatments | Patients eligible | Uptake of intervention | Absolute risk reduction | Death prevented or postponed1-150 | Proportion of overall deaths prevented or postponed |
|---|---|---|---|---|---|
| Acute MI | 15505 | – | 0.069 | 694 (366–1083) | 10% |
| Community CPR | 6357 | 0.5 | 0.056 | 178 (168–188) | – |
| Hospital CPR | 1355 | 0.95 | 0.150 | 193 (55–271) | – |
| Thrombolysis alone | 12181 | 0.01 | 0.030 | 4 (1–18) | – |
| Thrombolysis and aspirin | 12181 | 0.3 | 0.52 | 190 (88–369) | – |
| Aspirin alone | 12181 | 0.29 | 0.024 | 85 (33–148) | – |
| ACE inhibitor | 12181 | 0.16 | 0.0065 | 13 (5–30) | – |
| β Blocker | 12181 | 0.2 | 0.013 | 32 (16–59) | – |
| Secondary prevention post-MI | 36196 | – | 0.019 | 431 (152–877) | 6% |
| Aspirin alone | 36196 | 0.55 | 0.007 | 97 (22–177) | – |
| β Blocker alone | 36196 | 0.15 | 0.023 | 94 (23–55) | – |
| Aspirin and β blocker | 36196 | 0.05 | 0.029 | 39 (42–218) | – |
| ACE inhibitor | 36196 | 0.10 | 0.023 | 62 (11–222) | – |
| Simvastatin | 36196 | 0.10 | 0.006 | 17 (2–59) | – |
| Warfarin | 36196 | 0.05 | 0.010 | 15 (3–50) | – |
| Rehabilitation including exercise | 36196 | 0.19 | 0.020 | 117 (43–258) | – |
| Secondary prevention post-CABG/angioplasty | 11267 | 0.75 | 0.019 | 114 (49–243) | 2% |
| Angina | 156751 | – | 0.004 | 329 (36–686) | 5% |
| CABG surgery | 13384 | 1.00 | 0.010 | 131 (95–387) | – |
| Angioplasty | 6114 | 1.00 | 0.002 | 12 (0–26) | – |
| Unstable angina | 6450 | 1.00 | 0.005 | 34 (4–90) | – |
| Aspirin in community | 156751 | 0.33 | 0.004 | 152 (32–570) | – |
| Heart failure | 76978 | – | – | 563 (489–617) | 8% |
| Hospital | 9562 | 0.40 | 0.125 | 333 (105–738) | – |
| Community | 76978 | 0.20 | 0.030 | 362 (38–1316) | – |
| Hypertension | 1935200 | 0.62 | 0.003 | 590 (150–1132) | 9% |
| Total treatments | 2722 (1373–5986) | 40% |
↵1-150 Minimum and maximum estimates.
MI, myocardial infarction; CPR, cardiopulmonary resuscitation.