Table 2

Determinants of mortality during follow up in 111 medically treated elderly patients with aortic stenosis

Univariate analysisMultivariate analysis
Variable Total
(n)
Died
(n (%))
HR 95% CI HR 95% CI
Total11146 (44)
Age
 <80 years6022 (37)
 ⩾80 years5124 (47)1.60.9 to 2.91.00.5 to 1.9
Sex
 Male3513 (37)
 Female76 33 (43)1.10.5 to 2.00.80.4 to 1.7
Syncope
 No10142 (42)
 Yes104 (40)0.90.3 to 2.4
Angina or dyspnoea
 NYHA I/II5517 (31)
 NYHA III/IV5629 (52)2.01.1 to 3.61.60.8 to 3.0
Heart failure
 No8027 (34)
 Yes3119 (62)2.31.3 to 4.1
Previous infarct
 No8530 (35)
 Yes26 16 (62)2.31.3 to 4.3
LVH on ECG
 No7329 (40)
 Yes3817 (45)1.00.6 to 1.9
Atrial fibrillation
 No8633 (38)
 Yes2513 (52)1.40.7 to 2.6
AS ⩾75 mm Hg
 No8032 (40)
 Yes3114 (45)1.10.6 to 2.1
LV function
 Normal6613 (20)
 Impaired4533 (73)5.73.0 to 11.04.82.4 to 9.5
Mitral regurgitation
 Grade 0 or I6320 (32)
 Grade II4826 (54)2.51.4 to 4.52.01.1 to 3.8
  • AS, aortic stenosis (maximum gradient across aortic valve); CI, confidence interval; HR, hazard ratio; LV, left ventricular; LVH, left ventricular hypertrophy; NYHA, New York Heart Association.