Implications of targeting statin treatment at four CHD risk levels, showing the number needed to treat, cost effectiveness, and implications for the UK population
| CHD events per year | ||||
|---|---|---|---|---|
| 4.5% | 3.0% | 2.0% | 1.5% | |
| NNT for 5 years2-150 | 13 | 20 | 30 | 40 |
| Cost per life year gained† | £5100 | £8200 | £10700 | £12500 |
| Cumulative proportion of UK adults above CHD risk threshold | 5.1% | 8.2% | 15.8% | 24.7% |
| Annual cost of treatment if implemented fully in England | £549 m | £885 m | £1712 m | £2673 m |
↵2-150 Number needed to treat for 5 years to prevent one major coronary event; †For simvastatin treatment at 27.4 mg daily; m, million.