Table 2

Implications of targeting statin treatment at four CHD risk levels, showing the number needed to treat, cost effectiveness, and implications for the UK population

CHD events per year
NNT for 5 years2-150 13203040
Cost per life year gained £5100£8200£10700£12500
Cumulative proportion of UK adults above CHD risk threshold5.1%8.2%15.8%24.7%
Annual cost of treatment if implemented fully in England£549 m£885 m£1712 m£2673 m
  • 2-150 Number needed to treat for 5 years to prevent one major coronary event; For simvastatin treatment at 27.4 mg daily; m, million.