Mean haemodynamic values during exercise tolerance test
| Placebo | Mivazerol | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| HR (bpm) | SBP (mm Hg) | DBP (mm Hg) | RPP (bpm × mm Hg) | HR (bpm) | SBP (mm Hg) | DBP (mm Hg) | RPP (bpm × mm Hg) | ||
| Each minute | |||||||||
| Min 0 | 73.4 | 135.2 | 79.8 | 9853.6 | 64.6 | 123.7 | 77.4 | 8026.9 | |
| Min 1 | 91.4 | – | – | – | 84.8 | – | – | – | |
| Min 2 | 101.1 | – | – | – | 95.1 | – | – | – | |
| Min 3 | 103.6 | 153.3 | 83.2 | 15 896.5 | 96.8 | 141.6 | 79.0 | 13 787.6 | |
| Min 4 | 112.6 | – | – | – | 107.0 | – | – | – | |
| Min 5 | 118.7 | – | – | – | 111.9 | – | – | – | |
| Min 6 | 119.3 | 163.8 | 85.7 | 19 826.0 | 115.2 | 156.4 | 82.2 | 18 225.3 | |
| Specified time points | |||||||||
| Time to 1 mm ST depression | 116.8 | – | – | – | 111.1 | – | – | – | |
| Time to onset of angina | 117.3 | 153.3 | 85.4 | 18 660.3 | 114.0 | 155.8 | 82.2 | 17 934.6 | |
| Total exercise duration | 128.8 | 171.7 | 83.2 | 22 535.8 | 127.0 | 165.3 | 83.5 | 21 086.1 | |
| Maximum common time | 123.9 | – | – | – | 116.4 | – | – | – | |
HR, heart rate: SBP, systolic blood pressure; DBP, diastolic blood pressur; RPP, rate–pressure product.