Table 3

Detection of serum anti-M2 mAChR antibodies in chagasic patients subjected to different tests for dysautonomia

  • Chagasic patients (group I, n = 55; group II, n = 30) were subjected to a variety of tests for detection of cardiovascular dysautonomia. The presence of circulating anti-M2 mAChR antibodies in every patient was determined at 1/50 serum dilution byelisa as described in Methods.

  • Prevalence of antibodies in patients with normalv abnormal tests for dysautonomia were compared by χ2 test with Yates’ correction. Significantly different from normal test: *p < 0.00001;p < 0.02637; §p < 0.01322; p< 0.00009.

  • 3-151 Altered basal heart rate = bradycardia (< 55 beats/min).