Mean plasma lipid concentrations for the diet group (D) and the statin group (S) during the run in period (week 28) and post-statin period (week 48)
| Week | |||||||
|---|---|---|---|---|---|---|---|
| 12 | 16 | 20 | 24 | 28 | 48 | ||
| Total cholesterol (mmol/l) | D | 9.59 (0.85) | 9.52 (1.06) | 9.70 (1.09) | 9.49 (1.20) | 9.44 (1.27) | 9.34 (1.14) |
| S | 9.46 (1.16) | 6.90 (1.34)*** | 6.36 (1.50)*** | 5.72 (0.78)*** | 5.79 (0.75)2-151 *** | 9.13 (0.83)2-152 | |
| LDL cholesterol (mmol/l) | D | 7.84 (0.80) | 7.86 (0.91) | 7.76 (0.98) | 7.89 (0.83) | 7.86 (0.91) | 7.78 (0.98) |
| S | 7.81 (0.72) | 4.73 (0.54)*** | 4.53 (0.59)*** | 4.14 (0.52)*** | 4.19 (0.49)2-151 *** | 7.73 (0.91)2-152 | |
| HDL cholesterol (mmol/l) | D | 1.11 (0.49) | 1.16 (0.39) | 1.14 (0.39) | 1.11 (0.41) | 1.16 (0.47) | 1.03 (0.34) |
| S | 1.19 (0.39) | 1.32 (0.52) | 1.29 (0.49) | 1.29 (0.47) | 1.32 (0.54) | 0.98 (0.23)2-152 | |
| VLDL cholesterol (mmol/l) | D | 0.65 (0.31) | 0.49 (0.31) | 0.52 (0.23) | 0.47 (0.26) | 0.44 (0.16)2-151 | 0.49 (0.47) |
| S | 0.49 (0.18)* | 0.85 (0.047)** | 0.54 (0.18) | 0.28 (0.13)** | 0.34 (0.21) | 0.44 (0.39) | |
| Triglyceride (mmol/l) | D | 2.46 (0.62) | 2.53 (0.59) | 2.28 (0.49) | 2.35 (0.65) | 2.17 (0.59) | 2.48 (0.49) |
| S | 2.48 (0.65) | 3.90 (1.06)*** | 3.54 (0.62)*** | 2.07 (0.57) | 2.09 (0.57)2-151 | 2.22 (0.47) | |
Values are mean (SD).
↵2-151 p < 0.001, within group values for triglyceride, total cholesterol, and cholesterol fraction from week 12 to week 28 changes, by analysis of variance.
↵2-152 p < 0.001 values from week 28 to week 48, by Student'st test.
Significant same week, between group lipid comparisons using Student's t test are given by * for p < 0.05, ** for p < 0.01, and *** for p < 0.001.