Clinical characteristics of heart transplant candidates compared with normal controls
| Candidates | Normal | |
| Number of subjects | 38 | 26 |
| Age; mean in years (range) | 50.6 (34 to 61) | 47.3 (27 to 62) |
| Sex | ||
| Male | 30 (79%) | 20 (77%) |
| Female | 8 (21%) | 6 (23%) |
| Smoking status | ||
| Non-smokers | 10 (26%) | 21 (81%) |
| Ex-smokers (for more than one year) | 28 (74%) | 5 (19%) |
| Diagnosis | ||
| Ischaemic heart disease | 25 (66%) | |
| Dilated cardiomyopathy | 10 (26%) | |
| Valvar heart disease | 3 (8%) | |
| Haemoglobin (g/l) (mean (range)) | 140 (119 to 173) | |
| LVEF (mean (range)) | 12.8 (6% to 26%) | |
| Lung function (mean % predicted (SEM)) | ||
| FVC | 91.6 (2.3) | 102.9 (2.1)1-150 |
| FEV1 | 90.1 (2.2) | 105.2 (3.9)1-150 |
| FEV1/FVC | 93.1 (1.4) | 98.6 (1.8)1-150 |
| TLC | 91.4 (1.9) | 100.2 (3.3)1-150 |
↵1-150 Denotes significant difference between the two groups; p < 0.05.
LVEF, left ventricular ejection fraction; FVC, forced vital capacity; FEV1, forced expiratory volume in the first second; TLC, total lung capacity.