Table 3

Endothelium dependent and independent dilatation of the brachial artery and von Willebrand factor concentration according to degree of renal impairment

Controls First quartile Second quartile Third quartile Fourth quartile
GFR (ml/min)78 (62 to 93)49 (46 to 54)32 (31 to 36)24 (22 to 27)16 (14 to 18)
Baseline diameter (cm)0.48 (0.39 to 0.52)0.51 (0.45 to 0.55)0.53 (0.47 to 0.57)0.50 (0.45 to 0.52)0.51 (0.46 to 0.54)
Increase in velocity (%)208 (176 to 229)206 (190 to 225)202 (180 to 218)167 (151 to 215)178 (169 to 213)
EDD (%)6.5 (4.8 to 8.3)2.7 (0.7 to 6.7)2.3 (0.1 to 4.8)1.9 (1.5 to 4.3)2.8 (1.1 to 5.0)
EID (%)14.5 (10.6 to 19.0)11.0 (8.1 to 13.4)9.1 (6.2 to 11.0)9.8 (8.8 to 16.8)9.8 (7.6 to 14.6)
vWF (iu/dl)106 (87 to 138)255 (205 to 291)223 (185 to 276)273 (223 to 298)254 (209 to 292)
  • Results are expressed as median (interquartile range). Significance was assessed with the Kruskal-Wallis test.

  • EDD, endothelium dependent dilatation; EID, endothelium independent dilatation; GFR, glomerular filtration rate; vWF, von Willebrand factor.