Table 5

Age adjusted correlations of autonomic function with homeostatic function by diabetes status

Non-diabeticDiabetic
%SProinsulin%SProinsulin
rsp Valuersp Valuersp Valuersp Valuersp Valuersp Value
Spectral measures of heart rate variability
LF0.310.14−0.150.48−0.290.250.100.640.270.20−0.230.29
HF0.460.02−0.290.18−0.290.26−0.100.640.140.53−0.250.26
Non-spectral measures of heart rate variability
SDANN0.200.35−0.120.56−0.450.06−0.290.180.450.03−0.140.51
SD0.190.37−0.080.70−0.380.12−0.080.710.330.12−0.210.34
rMSSD0.310.14−0.230.29−0.270.28−0.200.350.170.43−0.120.58
pMN500.390.06−0.240.25−0.290.25−0.150.480.140.52−0.090.69
SDNN0.170.42−0.080.70−0.460.06−0.240.260.480.02−0.210.36
Clinical tests
Valsalva ratio0.030.90−0.110.620.240.33−0.450.030.100.63−0.070.74
Respiratory variation (beats/min)−0.240.26−0.090.670.140.58−0.060.77−0.070.75−0.100.67
30:15 heart rate ratio−0.240.25−0.020.930.140.59−0.180.390.460.02−0.210.34
Supine/standing fall in systolic pressure (mm Hg)−0.130.55−0.070.76−0.200.44−0.180.400.190.38−0.230.32
Increase in diastolic pressure; handgrip (mm Hg)−0.050.830.270.19−0.280.25−0.210.330.130.530.020.93
  • HF, high frequency; LF, low frequency; pNN50, proportion of adjacent RR intervals more than 50 ms different; rMSSD, root mean square of difference of successive RR intervals;r s, Spearman correlation coefficient; SD, mean of all five minute standard deviations of RR intervals; SDANN, standard deviation of five minute RR intervals; SDNN, standard deviation of all RR intervals from the mean.