Table 5

Coated stents

AuthorStentAnimal modelCoatingControlNeointimal thicknessDuration (weeks)
CoatedControl
divYsio Porcine coronary, matchedPCBare stent
Bare stent
0.14 (0.09)5-153
0.10 (0.08)5-153
0.15 (0.13)5-153
0.09 (0.07)5-153
 4
12
Kuiper21 Palmaz-SchatzRabbit iliac, porcine coronary, matchedPCBare stent0.20 (0.05)
0.44 (0.27)
0.23 (0.11)
0.47 (0.38)
 4
 4
van der Giessen9 WiktorPorcine coronary, matchedPGLA
PEO
Bare stent
Bare stent
0.46 (0.18)
2.36 (0.60)
0.08 (0.03)
0.38 (0.17)
 4
 4
Hardhammer17 Palmaz-SchatzPorcine coronary, matchedHeparinBare stent
Bare stent
0.26 (0.10)
0.15 (0.06)
0.11 (0.04)
0.20 (0.05)
 4
12
van der Giessen26 WallstentPorcine coronary, matchedBiogoldBare stent0.11 (0.04–0.17)5-151 0.10 (0.07–0.19)5-151 12
de Scheerder27 Not describedPorcine coronary, oversized injury modelPOP/MPDPOP stent0.99 (0.28)1.74 (0.84)6
Cox28 CookPorcine coronary, oversized injury modelCEL/HEP/METBare stent4
Lincoff23 WiktorPorcine coronary, oversized injury modelHMWPLLA/DEXPLLA stent
Bare stent
0.79 (0.44)5-152 0.81 (0.23)5-152
0.88 (0.31)5-152
4
Aggarwal34 CookRabbit iliac, balloon injury modelCEL/GPIIb/IIIaCEL ± anti CMV0.12 (0.04)0.11 (0.07)4
  • PC, phosphorylcholine; PGLA, polyglycolic/lactic acid; PEO, polyethyleneoxide; POP/MPD, polyorganophosphazene/methylpredisnolone; CEL/HEP/MET, cellulose/heparin/methotrexate; HMWPLLA/DEX, high molecular weight poly-L lactic acid/dexamethasone; CMV, cytomegalovirus.

  • 5-150 Representative values for the best and worst performing polymers are given;

  • 5-151 range;

  • 5-152 values calculated from fig 6 in Lincoffet al 23;

  • 5-153 for comparative purposes, the thickness of the wire struts have been deducted from the data.