Properties of isotopes used in PET imaging
Isotope | Half life (min) | Positron energy (MeV) | Mean range in tissue (mm) | Examples of labelled compounds | |||||
---|---|---|---|---|---|---|---|---|---|
Mean | Maximum | ||||||||
15O | 2.03 | 0.74 | 1.74 | 2.97 | H2 15O— blood flow 15O2—oxygen consumption C15O—blood volume | ||||
13N | 10.0 | 0.49 | 1.20 | 1.73 | 13NH3—blood flow | ||||
11C | 20.4 | 0.39 | 0.97 | 1.23 | 11C-HED—presynaptic catecholamine reuptake (uptake 1) 11C-CGP 12177—β adrenoceptors 11C-MQNB—muscarinic receptors11C-acetate—oxygen consumption | ||||
18F | 109.8 | 0.25 | 0.64 | 0.61 | 18F-FDG—glucose metabolism 18F-FDopa—dopamine storage |