Results of univariate Cox proportional hazards modelling of cardiovascular mortality
| Variable | Units/coding | Number | Hazard ratio | 95% CI | χ2(LRT) | df | p Value |
| Age (years) | 10 | 220 | 1.48 | 1.10 to 1.79 | 12.0 | 1 | <0.001 |
| Sex | 1=male | 220 | 1.14 | 0.74 to 1.75 | 0.347 | 1 | 0.56 |
| 2=female | |||||||
| Smoking | 1=never | 205 | 1.31 | 0.96 to 1.79 | 2.87 | 1 | 0.09 |
| 2=ex-smoker | |||||||
| 3=current smoker | |||||||
| Aetiology | CADv other | 220 | 1.45 | 0.93 to 2.22 | 2.61 | 1 | 0.11 |
| NYHA class | II to IV | 220 | 1.95 | 1.26 to 3.03 | 11.0 | 1 | <0.001 |
| Place of assessment | Inpatient vclinic | 220 | 4.70 | 1.90 to 11.63 | 17.8 | 1 | <0.001 |
| SBP | 10 mm Hg | 220 | 0.91 | 0.85 to 0.97 | 8.53 | 1 | 0.004 |
| DBP | 10 mm Hg | 220 | 0.85 | 0.75 to 0.97 | 6.55 | 1 | 0.01 |
| Crackles | 0=none | 219 | 2.25 | 1.61 to 3.15 | 25.6 | 1 | <0.001 |
| 1=basal | |||||||
| 2=more than basal | |||||||
| ECG rhythm | Sinus rhythmv atrial fibrillation | 217 | 1.65 | 1.00 to 2.73 | 4.11 | 1 | 0.04 |
| Cardiothoracic ratio (AP projection) | 10% | 101 | 1.78 | 1.18 to 2.69 | 7.48 | 1 | 0.006 |
| Pulmonary congestion | Score 1 (none) to 5 (alveolar oedema) | 215 | 1.31 | 1.03 to 1.66 | 5.61 | 1 | 0.02 |
| Sodium (mmol/l) | 218 | 0.93 | 0.89 to 0.98 | 6.28 | 1 | 0.01 | |
| Urea (mmol/l [log]3-150) | 218 | 1.47 | 1.16 to 1.85 | 10.5 | 1 | 0.001 | |
| Creatinine (mol/l [log]3-150) | 218 | 2.56 | 1.88 to 3.47 | 29.9 | 1 | <0.001 | |
| LV systolic function | Impaired vnormal | 199 | 0.80 | 0.43 to 1.47 | 0.61 | 1 | 0.43 |
| FS (%) | 80 | 1.03 | 0.99 to 1.08 | 1.99 | 1 | 0.19 | |
| LVEDD (cm) | 102 | 0.77 | 0.51 to 1.16 | 1.56 | 1 | 0.21 | |
| LVESD (cm) | 102 | 0.72 | 0.50 to 1.04 | 3.08 | 1 | 0.08 |
↵3-150 Hazard ratio for these variables refers to the ratio of hazard for a doubling in the serum concentration.
AF, atrial fibrillation; CAD, coronary artery disease; CI, confidence interval; DBP, diastolic blood pressure; df, degrees of freedom; FS, fractional shortening; LRT, likelihood ratio test; LV, left ventricular; LVEDD, left ventricular end diastolic diameter; LVESD, left ventricular end systolic diameter; SBP, systolic blood pressure; SR, sinus rhythm.