Table 1

Risk factors for infective endocarditis and underlying conditions

Risk factors and underlying conditions Period 1980–1987 (87 episodes), n (%) Period 1988–1995 (125 episodes), n (%) p Value
Cardiac and/or non-cardiac risk factors and conditions66 (76)107 (86)0.07
Cardiac risk factors51 (59)82 (66)NS
 Pre-existing valvar heart disease34 (39)58 (46)NS
 Congenital heart disease4 (5)4 (3)NS
 Artificial heart valve15 (17)21 (17)NS
Non-cardiac risk factors and conditions31 (36)54 (43)NS
 Intravenous drug use6 (7)16 (13)0.17
 HIV2 (2)8 (6)0.17
 Renal insufficiency14 (16)23 (18)NS
 Diabetes mellitus11 (13)16 (13)NS
 Pregnancy01 (1)NS
 Cancer7 (8)15 (12)NS