Table 1

The Duke criteria for endocarditis

Diagnosis is:
 • definite (by pathology or clinically), possible, or rejected
“Definite” clinical diagnosis by: 2 major, 1 major/3 minor or 5 minor criteria  (extremely rare)
Major criteria:
 • positive blood culture (⩾ 2) of typical bacteria
 • vegetation, abscess or prosthesis dehiscence on echo
 • new valvar regurgitation
Minor criteria:
 •  predisposition, fever, embolic/vascular phenomenon, immunologic signs (including glomerular nephritis, rheumatoid factor, Osler nodes, Roth spots), serology consistent with endocarditis, blood cultures compatible but atypical for endocarditis