Table 3

Adjusted effect of early thrombolysis

Mean infarct sizeMean ejection fraction
FactorEffect of variable3-150p ValueEffect of variable3-150p Value
Unadjusted3-151
 ⩾ 2 h to thrombolysis3.1  (1.3)0.018−3.2  (0.9)0.0004
Adjusted3-151
 ⩾ 2 h to thrombolysis2.9 (1.2)0.018−3.1 (0.8)0.0002
 Previous MI8.3 (1.5)< 0.0001−5.8 (1.0)< 0.0001
 Anterior MI16.7 (1.1)< 0.0001−11.1 (0.8)< 0.0001
 t-PA−3.5 (1.3)0.0050.9 (0.8)0.33
 Poloxamer 188−1.6 (1.2)0.18−1.4 (0.8)0.079
  • 3-150 Data refer to absolute changes in percentage (mean (SEM));

  • 3-151 changes relative to patients treated for less than two hours.