Table 2

Effects of normal saline on eight control subjects

Baseline Normal saline
Heart rate (beats/min)70 (4)69 (5)
Mean blood pressure (mm Hg)110 (4)112 (5)
Proximal artery segment (mm)3.04 (0.29)3.00 (0.30)
Distal artery segment (mm)1.52 (0.14)1.56 (0.16)
PVi (cm)16.5 (4.0)14.3 (3.1)
CBF (ml/min)80 (8)63 (9)
CVR (mm Hg/ml/min)2.17 (0.60)2.40 (0.68)
Plasma big ET-1 (fmol/ml)0.27 (0.02)0.25 (0.06)
  • Values are mean (SEM). There was no significant change between baseline and after normal saline administration.

  • CBF, coronary blood flow of the left anterior descending artery; CVR, coronary vascular resistance of the left anterior descending artery; ET-1, endothelin-1; PVi, peak velocity integral.