Table 3

Complex/significant congenital heart disease recognised prenatally, followed by termination of pregnancy, 1996

Patient Cardiac lesions Chromosomes
1HLHSN
2HLHSN
3HLHSN
4HLHSN
5HLHSN
6HLHS-EFE, tiny LVN
7LV hypoplasia, aortic hypoplasia, LVH+N
8Critical aortic stenosis—very small LV, EFEN
9Hypoplastic LV, DORV, mitral atresiaN
10Tetralogy of Fallot, small LV, pulmonary atresia,  cleft lip and palateN
11Multiple VSDs, cleft lip and palateN
12Severe Ebstein's anomalyTranslocation, chromosome 10
13TGA, pulmonary atresia, renal agenesisN
14Large confluent VSD, severe aortic hypoplasia,  tetralogy of FallotTrisomy 18
15Perimembranous VSD, pulmonary atresiaTrisomy 21
16CAVSD, hypoplastic LVTrisomy 21
17CAVSD, hypoplastic LV, DORVTrisomy 21
18CAVSD, hypoplastic LVPartial deletion, chromosome 6
19CAVSD, hypoplastic LV, TGAN
20CAVSD, pulmonary atresiaN
21CAVSD, TGAN
22CAVSD, LVOTO, renal agenesisN
23PAVSD, hypoplastic LVTrisomy 21
  • Total: five major and two minor chromosomal problems, two lethal non-cardiac abnormalities, three non-cardiac surgical abnormalities.

  • CAVSD, complete atrioventricular septal defect; DORV, double outlet right ventricle; EFE, endocardial fibroelastosis; HLHS, hypoplastic left heart syndrome; LV, left ventricle; LVH, left ventricular hypertrophy; LVOTO, left ventricular outflow tract obstruction; N, normal; PAVSD, partial atrioventricular septal defect; TGA, transposition of the great arteries.