Baseline characteristics of patients with diabetes mellitus in the MRC/BHF heart protection study
| Characteristic at entry | Type 1 (n=615) | Type 2 (n=5348) |
| Disease history | ||
| Myocardial infarction | 30 (5%) | 1095 (20%) |
| Other CHD | 31 (5%) | 822 (15%) |
| Other cardiovascular | 124 (20%) | 948 (18%) |
| No cardiovascular | 430 (70%) | 2483 (46%) |
| Treated hypertension | 118 (19%) | 2279 (43%) |
| Duration of diabetes (years) | 28.6 (0.5) | 9.3 (0.1) |
| Age (years) | 52.6 (0.3) | 63.2 (0.1) |
| ⩽ 65 | 564 (92%) | 3082 (58%) |
| > 65 | 51 (8%) | 2266 (42%) |
| Total cholesterol (mmol/l) | 5.52 (0.04) | 5.68 (0.01) |
| ⩽ 5.5 | 315 (51%) | 2464 (46%) |
| > 5.5 ⩽ 7.0 | 257 (42%) | 2349 (44%) |
| > 7.0 | 43 (7%) | 535 (10%) |
| LDL cholesterol (mmol/l)1-150
| 3.01 (0.03) | 3.24 (0.01) |
| ⩽ 3.0 | 330 (54%) | 2131 (40%) |
| > 3.0 ⩽ 3.5 | 113 (18%) | 1306 (24%) |
| > 3.5 | 172 (28%) | 1911 (36%) |
| HDL cholesterol (mmol/l)1-150
| 1.40 (0.02) | 1.02 (0.00) |
| ⩽ 1.0 | 96 (16%) | 3023 (57%) |
| > 1.0 | 519 (84%) | 2325 (43%) |
| Triglycerides (mmol/l) | 1.24 (0.03) | 2.38 (0.02) |
| ⩽ 2.0 | 526 (86%) | 2690 (50%) |
| > 2.0 | 89 (14%) | 2658 (50%) |
| HbA1c (%)1-151 | 7.90 (0.09) | 7.04 (0.03) |
| ⩽ 7.0 | 235 (38%) | 3025 (57%) |
| > 7.0 | 379 (62%) | 2318 (43%) |
Values are either n (%) or mean (SE).
↵1-150 Corresponding differences between those with type 1 and type 2 diabetes were seen in blood concentrations of apolipoprotein B (1.01 (0.01) g/lv 1.11 (0.003) g/l) and of apolipoprotein A1 (1.33 (0.01) g/l v 1.18 (0.003) g/l).
↵1-151 HbA1C was measured by a turbidimetric method on Beckman Synchron CX autoanalysers (manufacturer's normal range 2.9–4.6%).