Table 2

Morphometric evaluation of myocardial tissue on light microscopy (haematoxylin and eosin, and picrosirius red)

Controls (n=12)DCM (n=12)p Value
Fractional area (%) of myocardial tissue83.65  (5.04)82.93  (6.33)NS
Number of nuclei/mm2 of myocardial tissue668.22 (131.29)392.83 (71.78)0.001
Nucleus diameter (μm)8.35 (1.06)10.45 (1.98)0.01
Nucleus area (μm2)55.56 (14.08)88.27 (33.12)0.005
Myocyte diameter (μm)16.74 (1.17)22.89 (3.30)0.002
Fibrosis area (%)13.39 (9.55)18.71 (7.76)NS
  • Values are mean (SD) or n.

  • DCM, dilated cardiomyopathy.