Absolute risk, benefit, odds ratios (OR), and 95% confidence intervals (CI) for cardiovascular events, myocardial infarctions, strokes, and all cause mortality
Absolute risk in control group (%/year) | Absolute benefit from aspirin (%/year) | OR | 95% CI | |
Cardiovascular events | ||||
US4 | 0.67 | 0.11 | 0.82 | 0.71 to 0.96 |
UK10 | 1.34 | −0.04 | 1.02 | 0.82 to 1.27 |
TPT5 | 1.71 | 0.41 | 0.74 | 0.57 to 0.97 |
HOT6 | 1.05 | 0.16 | 0.85 | 0.73 to 0.99 |
Weighted mean | 0.92 | 0.13 | 0.85 | 0.78 to 0.94 |
Myocardial infarction | ||||
US4 | 0.44 | 0.18 | 0.56 | 0.48 to 0.71 |
UK10 | 0.93 | 0.03 | 0.96 | 0.73 to 1.25 |
TPT5 | 1.33 | 0.31 | 0.76 | 0.57 to 1.03 |
HOT6 | 0.36 | 0.13 | 0.65 | 0.49 to 0.85 |
Weighted mean | 0.52 | 0.15 | 0.70 | 0.62 to 0.79 |
Strokes | ||||
US4 | 0.18 | −0.04 | 1.22 | 0.93 to 1.59 |
UK10 | 0.41 | −0.07 | 1.16 | 0.80 to 1.68 |
TPT5 | 0.32 | 0.10 | 0.69 | 0.38 to 1.26 |
HOT6 | 0.42 | 0.01 | 0.98 | 0.78 to 1.24 |
Weighted mean | 0.29 | −0.02 | 1.06 | 0.91 to 1.24 |
All cause mortality | ||||
US4 | 0.41 | 0.02 | 0.96 | 0.79 to 1.15 |
UK10 | 1.59 | 0.16 | 0.88 | 0.71 to 1.09 |
TPT5 | 1.31 | −0.05 | 1.03 | 0.78 to 1.36 |
HOT6 | 0.86 | 0.06 | 0.93 | 0.79 to 1.09 |
Weighted mean | 0.73 | 0.05 | 0.94 | 0.85 to 1.04 |