|
Absolute risk in control group (%/year)
|
Absolute benefit from aspirin (%/year)
|
OR
|
95% CI |
Cardiovascular events
|
US4
| 0.67 | 0.11 | 0.82 | 0.71 to 0.96 |
UK10
| 1.34 | −0.04 | 1.02 | 0.82 to 1.27 |
TPT5
| 1.71 | 0.41 | 0.74 | 0.57 to 0.97 |
HOT6
| 1.05 | 0.16 | 0.85 | 0.73 to 0.99 |
Weighted mean
|
0.92
|
0.13
|
0.85
|
0.78 to 0.94
|
| |
Myocardial infarction
|
US4
| 0.44 | 0.18 | 0.56 | 0.48 to 0.71 |
UK10
| 0.93 | 0.03 | 0.96 | 0.73 to 1.25 |
TPT5
| 1.33 | 0.31 | 0.76 | 0.57 to 1.03 |
HOT6
| 0.36 | 0.13 | 0.65 | 0.49 to 0.85 |
Weighted mean
|
0.52
|
0.15
|
0.70
|
0.62 to 0.79
|
| |
Strokes
|
US4
| 0.18 | −0.04 | 1.22 | 0.93 to 1.59 |
UK10
| 0.41 | −0.07 | 1.16 | 0.80 to 1.68 |
TPT5
| 0.32 | 0.10 | 0.69 | 0.38 to 1.26 |
HOT6
| 0.42 | 0.01 | 0.98 | 0.78 to 1.24 |
Weighted mean
|
0.29
|
−0.02
|
1.06
|
0.91 to 1.24
|
| |
All cause mortality
|
US4
| 0.41 | 0.02 | 0.96 | 0.79 to 1.15 |
UK10
| 1.59 | 0.16 | 0.88 | 0.71 to 1.09 |
TPT5
| 1.31 | −0.05 | 1.03 | 0.78 to 1.36 |
HOT6
| 0.86 | 0.06 | 0.93 | 0.79 to 1.09 |
Weighted mean
|
0.73
|
0.05
|
0.94
|
0.85 to 1.04
|