Table 3

Absolute risk, harm, odds ratios (OR), and 95% confidence intervals (CI) for best overall estimate of haemorrhage, major bleeds, bleeds requiring transfusion, and non-minor bleeds

Absolute risk in control group (%/year) Absolute harm from aspirin (%/year) OR 95% CI
Best overall estimate of haemorrhage
US4 0.050.041.701.08 to 2.66
UK10 0.100.011.050.49 to 2.21
TPT5 0.460.231.531.01 to 2.32
HOT6 0.180.161.901.42 to 2.54
Weighted mean 0.13 0.09 1.69 1.38 to 2.07
Major non-cerebral bleeds
US4 0.050.041.701.08 to 2.66
TPT5 0.050.051.960.63 to 6.09
Weighted mean 0.05 0.04 1.73 1.14 to 2.63
Non-minor bleeds
TPT5 0.460.231.531.01 to 2.32
HOT6 0.180.161.961.42 to 2.54
Weighted mean 0.22 0.18 1.77 1.40 to 2.25