Initial CABG + AVR | Initial CABG + later AVR if necessary | Initial CABG + AVR is associated with: | |||||
---|---|---|---|---|---|---|---|
Unnecessary AVR | Excess mortality | ||||||
Total number of patients | 100 | 100 | |||||
1. At 30 days | |||||||
(a) Mortality | 8 | 3 | 100 | 5 | |||
2. At 3 years | |||||||
(a) Mortality | 185-151 | 95-150 | |||||
(b) Late AVR in survivors | 0 | 0 | 100 | 9 | |||
3. At 5 years | |||||||
(a) Mortality | 305-151 | 155-150 | |||||
(b) Late AVR/reop AVR in survivors | 0 | 15 | |||||
(c) 15% 30 day mortality of late AVR | 0 | 2 | |||||
(d) Total deaths | 30 | 17 | 85 | 13 | |||
4. At 10 years | |||||||
(a) Mortality | 605-151 | 305-150 | |||||
(b) Late AVR/reop AVR in survivors | 6 | 465-152 | |||||
(c) 15% 30 day mortality of late AVR | 1 | 7 | |||||
(d) Total deaths | 61 | 37 | 54 | 24 |
↵5-150 Mortality after CABG
↵5-151 Mortality after CABG+AVR
↵5-152 Events (death+AVR) at 10 years is 65%; for this analysis it was considered 65% of 70 survivors (that is, 46) would need late AVR which is most likely an overestimate.
Repeat revascularisation similar in both groups; its incidence and associated mortality
are not included.
Ten year complications after revascularisation and with prosthetic heart valves are not included.
Mortality at time of reoperation are included in the 5 and 10 year data. The assumed 15% mortality for reoperation is probably too high.