Evolution to dilated cardiomyopathy in patients with acute myocarditis
Reference | Number of patients | Diagnosis | Evolution to DCM (%) | Mean follow up or range |
Bengtsson 196630 | 90 | Clinical | 15 | 60 months |
Helin 196831 | 12 | Clinical | 0 | 7 months |
Sainani 196832 | 19 | Clinical | 0 | 3 months |
Smith 197033 | 42 | Clinical | 7 | 84 months |
Gerzen 197234 | 18 | Clinical | 28 | 12 months |
Levi 197735 | 10 | Clinical | 0 | 42–68 months |
Kitaura 197936 | 11 | Histology | 27 | 18–156 months |
Edwards 198237 | 5 | Histology | 20 | 6–12 months |
Kayakawa 198338 | 20 | Clinical | 30 | 49 months |
Fenoglio 198321 | 18 | Histology | 17 | 12 months |
Kayakawa 198439 | 10 | Clinical | 30 | 55 months |
Daly 198440 | 9 (IS 9) | Histology | 22 | 6 months |
Dec 198513 | 18 | Histology | 11 | 6–12 months |
Das 198541 | 18 | Clinical | 11 | 54 months |
Billingham 198642 | 20 (IS 15) | Histology | 40 | 5 months |
Giesecke198724 | 45 | Clinical | 11 | 3 months |
Quigley 198712 | 23 | Histology | 52 | 43 months |
Weiss 198743 | 13 (IS 1) | Histology | 46 | 36 months |
Anderson 198744 | 10 | Histology | 20 | 6–12 months |
Sekiguchi198817 | 20 | Histology | 10 | 49 months |
Salvi 199045 | 38 (IS 28) | Histology | 29 | 49 months |
Davidoff 199146 | 36 (IS 20) | Histology | 19 | 30 months |
Sekiguchi 199447 | 90 | Histology | 14 | 45 months |
Maisch 199448 | 21 | Histology | 28 | 6 months |
Mason 199527 | 47 | Histology | 17 | 52 months |
Sinagra 199718 | 56 (IS 36) | Histology | 39 | 48 months |
Total | 719 | Mean 21% | Mean f/u 33 months |
Published data on the incidence of progression to dilated cardiomyopathy in patients with clinical or histological diagnosis of acute myocarditis of viral or unknown origin.
DCM, dilated cardiomyopathy; f/u, follow up; IS, number of patients treated with immunosuppressive drugs (no placebo controlled data).