Table 1

Adjunctive pharmacotherapy during and after primary angioplasty

Drug Target Acute Chronic
AspirinPlatelets++
Glycoprotein IIa/IIIb antagonistsPlatelets+
Clopidogrel (after stenting)Platelets+4 weeks
Nitrates ic and/or ivVasospasm+
HeparinThrombin+
β Adrenergic blockersSympathetic receptor++
ACE inhibitorHeart failure prevention?+
  • Do not forget adequate sedation and pain relief!

  • ic, intracoronary; iv, intravenous; ACE, angiotensin converting enzyme.