Table 1

Comparison of calcific aortic valve disease and atherosclerosis

Calcific aortic valve disease Atherosclerosis
Clinical
 Increased prevalence with age++++++++
 Association with clinical factors++++++++
Pathologic
 Inflammatory cells++++++
 Lipid infiltration++++++
 Calcification++++++
Genetic factors?++++
Mechanism of clinical eventsLeaflet stiffnessPlaque instability