Comparison of calcific aortic valve disease and atherosclerosis
Calcific aortic valve disease | Atherosclerosis | |
Clinical | ||
Increased prevalence with age | ++++ | ++++ |
Association with clinical factors | ++++ | ++++ |
Pathologic | ||
Inflammatory cells | +++ | +++ |
Lipid infiltration | +++ | +++ |
Calcification | ++++ | ++ |
Genetic factors | ?+ | +++ |
Mechanism of clinical events | Leaflet stiffness | Plaque instability |