Table 1

Demographic, haemodynamic, and scintigraphic variables in a case of isolated left ventricular non-compaction

Variable Baseline After carvedilol p Value
Age (years)0.331.83
Weight (kg)6.39.6
BSA (m2)0.310.44
LVEF (%)3057
LVEDV (ml)1-150 47 (347%)28 (126%)
LVESV (ml)3312
LVEDP (mm Hg)138
Mean PAP (mm Hg)1812
LV mass (g)59.137.3
LV mass to EDV ratio1.261.33
Mean (SD) area of non-compaction (%)1-151 64.2 (17.4)47.3 (11.0)0.0598
Mean (SD) LV wall thickening (%)1-152
 Septum27.0 (11.0)30.5 (4.8)NS
 Anterior wall0.8 (15.0)29.1 (24.8)< 0.01
 Lateral wall1.9 (12.8)32.7 (28.7)< 0.01
 Inferior wall6.5 (17.0)59.2 (32.1)< 0.01
Myocardial tracer uptake (lateral/septum)
 123I-MIBG delayed0.681.2
201T11.061.34
123I-BMIPP0.891.12
123I-MIBG washout rate (%)1-153
 Septum2519
 Lateral wall5123
  • 1-150 Per cent of normal values in parentheses.

  • 1-151 Mean values of per cent area of non-compaction of total ventricular wall in apical, mid-ventricular, and basal short axis echocardiographic images at end diastole and end systole.

  • 1-152 Per cent wall thickening defined as [wall thickness at systole minus wall thickness at diastole]/[wall thickness at diastole] × 100. Average values of measurements at four points in each segment are shown.

  • 1-153 MIBG washout rate defined as [MIBG early uptake minus MIBG delayed uptake]/[MIBG early uptake] × 100.

  • BSA, body surface area;

  • 123I-BMIPP,

  • 123I-β-methyliodophenylpentadecanoic acid;

  • 123I-MIBG,

  • 123I-metaiodobenzylguanidine; LV, left ventricular; LVEDP, left ventricular end diastolic pressure; LVEDV, left ventricular end diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end systolic volume; PAP, pulmonary artery pressure.