Results of endocrine, blood pressure, and renal investigations in the three groups
| Normal controls | p Value (A) | Premature hypertensive | p Value (B) | Middle aged hypertensive | |
| Male patients | |||||
| Cortisol metabolites (μg/day) | 7270 (1788) | 0.0001 | 13 332 (6472) | 0.002 | 8315 (3565) |
| Androgen metabolites (μg/day) | 2783 (750) | 0.2 | 3801 (2015) | 0.03 | 2392 (1373) |
| ABPM 24 h systolic (mm Hg) | 116.2 | < 0.0001 | 147.5 | 0.27 | 158.9 |
| ABPM 24 h diastolic (mm Hg) | 73.8 | 0.005 | 89.3 | 0.45 | 95.2 |
| 24 h urinary sodium (mmol) | 147 (32) | 124 (26) | 167 (57) | ||
| 24 h urinary potassium (mmol) | 69 (27) | 88 (14) | 72 (22) | ||
| 24 h urine volume (ml) | 1746 (466) | 1792 (629) | 1668 (280) | ||
| Female patients | |||||
| Cortisol metabolites (μg/day) | 4588 (1480) | < 0.0001 | 11 016 (4261) | 0.02 | 7613 (2507) |
| Androgen metabolites (μg/day) | 1687 (636) | 0.002 | 2958 (1672) | 0.0003 | 1373 (748) |
| ABPM 24 h systolic (mm Hg) | 113.4 | 0.0002 | 148 | 0.52 | 142.5 |
| ABPM 24 h diastolic (mm Hg) | 70.7 | < 0.0001 | 98.7 | 0.1 | 85 |
| 24 h urinary sodium (mmol) | 142 (44) | 132 (36) | 148 (45) | ||
| 24 h urinary potassium (mmol) | 76 (21) | 87 (18) | 75 (15) | ||
| 24 h urine volume (ml) | 1702 (842) | 1640 (603) | 1689 (889) | ||
Values are mean (SD).
(A), p value between normal controls and premature hypertensive patients; (B), p value between premature hypertensive and middle aged hypertensive patients.
ABPM, ambulatory blood pressure monitoring.