Systemic haemodynamic and coronary diameter and blood flow variables
| HR (beats/min) | MAP (mm Hg) | Coronary diameter (mm) | Coronary blood flow (ml/min) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Proximal segments | Distal segments | ||||||||
| Baseline before L-NMMA | 68 (2) | 108 (4) | 3.00 (0.09) | 1.64 (0.06) | 79.3 (7.5) | ||||
| Low MgSO4 | 69 (2) | 105 (4) | 3.03 (0.09) | 1.67 (0.06) | 82.8 (7.3) | ||||
| High MgSO4 | 68 (3) | 105 (4) | 3.11 (0.09)1-150 1-151 | 1.77 (0.07)1-150 1-151 | 101.4 (9.9)1-150 1-151 | ||||
| Baseline after L-NMMA | 67 (2) | 108 (4) | 2.89 (0.09)1-160 | 1.58 (0.06)1-160 | 68.3 (6.1)1-160 | ||||
| Low MgSO4 | 68 (2) | 106 (4) | 2.93 (0.08) | 1.62 (0.06) | 71.7 (7.4) | ||||
| High MgSO4 | 67 (3) | 106 (3) | 3.01 (0.09)1-150 1-151 | 1.67 (0.06)1-150 1-152 | 86.2 (8.3)1-150 1-151 | ||||
| Glyceryl trinitrate | 75 (3)1-153 | 98 (4)1-154 | 3.26 (0.09)1-153 | 1.95 (0.06)1-153 | 98.4 (12.0)†† | ||||
Values are mean (SEM).
Low MgSO4 was at a dose of 0.02 mmol/min; high MgSO4 was at a dose of 0.2 mmol/min.
HR, heart rate; L-NMMA, NG-monomethy-L-arginine; MAP, mean arterial pressure.
↵1-150 p < 0.001 v baseline;
↵1-151 p < 0.01v low MgSO4;
↵1-152 p < 0.05v low MgSO4;
↵1-160 p < 0.05v baseline before L-NMMA;††p < 0.05v others except high MgSO4;
↵1-153 p < 0.001 v others;
↵1-154 p < 0.01v others.