Carriage of interleukin 1 receptor antagonist gene (IL-1RN) alleles in the Sheffield and Leicester restenosis and non-restenosis cohorts
| Leicester SVD and MVD | Sheffield SVD | |||||
|---|---|---|---|---|---|---|
| 11/12 2-150 | 22 2-151 | 11/12 2-150 | 22 2-151 | |||
| Restenosis (raw data) | 46 | 3 | 16 | 0 | ||
| Non-restenosers (raw data) | 58 | 10 | 25 | 7 | ||
| p Value | 0.1691 | 0.0384 | ||||
| Odds ratio (95% CI) | 2.6 (0.7 to 10.2) | N/A | ||||
| MH p value | 0.0196 | N/A | ||||
↵2-150 11/12, raw numbers of 1,1 and 1,2 alleles at IL-1RN (VNTR). Allele 1 has four repeats and allele 2 has two repeats of 86 base pairs.
↵2-151 22, raw numbers of 2,2 homozygotes at IL-1RN (VNTR).
N/A, Odds ratio and p value not applicable as one of the values in the contingency table is 0.
MH, Mantel–Haenzsel summary statistic; MVD, multiple vessel disease; SVD, single vessel disease.