Characteristic | Pravastatin group | Placebo group | p Value |
Baseline | |||
Total cholesterol | 5.90 (0.14) | 5.97 (0.14) | NS |
HDL | 1.20 (0.05) | 1.21 (0.05) | NS |
LDL | 3.80 (0.16) | 4.01 (0.14) | NS |
Triglycerides | 2.15 (0.22) | 1.72 (0.12) | NS |
Endothelial function testing | |||
Total cholesterol | 4.47 (0.10) | 5.87 (0.13) | < 0.001 |
HDL | 1.34 (0.08) | 1.23 (0.05) | NS |
LDL | 2.42 (0.11) | 3.79 (0.13) | < 0.001 |
Triglycerides | 1.62 (0.18) | 1.82 (0.18) | NS |
White blood cell count (109) | 7.45 (0.48) | 6.86 (0.13) | NS |
Platelet count (109) | 245 (5) | 242 (5) | NS |
Change from baseline to endothelial function testing | |||
Total cholesterol | −1.43 (0.12) | −0.11 (0.10) | < 0.001 |
HDL | 0.15 (0.06) | 0.01 (0.04) | < 0.05 |
LDL | −1.26 (0.16) | −0.18 (0.09) | < 0.001 |
Triglycerides | −0.47 (0.11) | −0.11 (0.11) | < 0.001 |
Values are mean (SEM), mmol/l.
HDL, high density lipoprotein; LDL, low density lipoprotein.