Table 2

The recognised markers of risk in HCM and their sensitivity, specificity, positive and negative predictive accuracy (PPA and NPA)

Risk factorSensitivity (%)Specificity (%)PPA (%)NPA (%)
*Figures provided are for the risk of death from all causes rather than sudden death only.
†Figures provided are for risk of sudden death and/or appropriate ICD discharge.
‡In this data set from Elliott and colleagues, family history and syncope were combined in order to achieve statistical significance of relative risk.
LVH, left ventricular hypertrophy; NSVT, non-sustained ventricular tachycardia; VF, ventricular fibrillation; VT, ventricular tachycardia.
Abnormal blood pressure response: <40 years old1975661597
NSVT: adult <45 years old1869802297
NSVT: ≤21 years old23<1089<1085
Inducible VT/VF: High risk populationw3082681798
*Syncope: <45 years old335822586
*Family history: at least one unexplained sudden death ± HCM342792888
†LVH ≥3 cm1726881395
†‡Two or more risk factors245902396