Table 8

Management of opportunistic infections after cardiac transplantation

OrganismTestTreatment
CMV, cytomegalovirus; CT computed tomography; IFT immunofluoresence test; CFT, complement fixation test.
CytomegalovirusIE-Gene, PCR, IgMGancyclovir, if severe additional CMV antibodies
Herpes simplex virusIgMAciclovir
Varicella-zoster virusIgMAciclovir
Hepatitis B virusIgMLamivudine
Legionella speciesUrine antigen, x rayErythromycin
Mycobacterium tuberculosis Ziehl-NeelsonRifampicin, isoniazid, myambutol
Nocardia asteroides Brain CTSulfamethoxazole/trimethoprim
Pneumocystis carinii x raySulfamethoxazole/trimethoprim
Toxoplasma gondii X ray, IFT, CFT, IgA, IgMPyrimethamine + sulfadiazine, folic acid
Candida albicansDirectFluconazole, itraconazole
Aspergillus fumigatus X rayItraconazole, amphotericin B, flucytosine
Cryptococcus neoformans Brain CTItraconazole, amphotericin B, flucytosine, or fluconazole
Listeria monocytogenes CNS: ampicillin + gentamycin