Baseline characteristics of patients with primary pulmonary hypertension and chronic thromboembolic pulmonary hypertension
| Variables | All patients (n=30) | PPH (n=14) | CTEPH (n=16) |
|---|---|---|---|
| Data are mean (SEM) or n. | |||
| *p<0.05 v PPH. | |||
| CO, cardiac output; CTEPH, chronic thromboembolic pulmonary hypertension; MPAP, mean pulmonary arterial pressure; NYHA, New York Heart Association; PCWP, pulmonary capillary wedge pressure; PPH, primary pulmonary hypertension; PVR, pulmonary vascular resistance; RAP, mean right atrial pressure. | |||
| Demographics | |||
| Age (years) | 51 (3) | 43 (5) | 59 (4)* |
| Male/female (n) | 10/20 | 6/8 | 4/12 |
| NYHA functional class (n) | |||
| II | 9 | 4 | 5 |
| III | 21 | 10 | 11 |
| Baseline haemodynamics | |||
| MPAP (mm Hg) | 42 (3) | 48 (3) | 37 (4)* |
| CO (l/min/m2) | 3.7 (0.2) | 3.7 (0.4) | 3.8 (0.4) |
| PVR (Wood units) | 13.5 (1.4) | 12.9 (1.8) | 9.3 (2.2) |
| RAP (mm Hg) | 5 (1) | 4 (1) | 5 (1) |
| PCWP (mm Hg) | 8 (1) | 7 (1) | 9 (1) |
| Drug treatment (n) | |||
| Anticoagulant agents | 28 | 12 | 16 |
| Digitalis | 9 | 4 | 5 |
| Diuretics | 12 | 6 | 6 |
| Calcium antagonists | 2 | 1 | 1 |