Table 4

Effect of amiodarone versus other antiarrhythmic agents in placebo controlled trials

OutcomeNumber of trialsAmiodarone estimate (%), mean (95% CI)Other active drugs* estimate (%), mean (95% CI)Treatment difference (%), mean (95% CI)p Value
*Other active drugs are digoxin, verapamil, propafenone, quinidine, procainamide, and flecainide.
Sinus rhythm2050.0 (6.7 to 93.3)47.2 (1.84 to 92.6)2.7 (−51.2 to 56.7)0.64
Mortality202.12 (0.68 to 3.56)2.29 (0.88 to 3.69)−0.17 (−1.66 to 1.32)0.38