Comparison of pre-interventional values between patients with normal and abnormal multimer pattern. Normal ranges were established at authors' institutions
| n | Age (years) | Heart murmur II°/III°/IV° | Qp/Qs | Platelets (×103/μl) | aPTT (s) | VWF:Ag (U/l) | VWF:CB (U/l) | VWF:CB/ VWF:Ag | |
|---|---|---|---|---|---|---|---|---|---|
| Values are median (range). | |||||||||
| aPPT, activated partial thromboplastin time; Qp/Qs, flow ratio of the pulmonary and systemic circulations, determined at cardiac catheterisation; VWF:Ag, von Willebrand antigen; VWF:CB, von Willebrand collagen binding capacity. | |||||||||
| Normal multimers | 8 | 5.6 (1.2–18.7) | 4/2/2 | 1.34 (1.00–1.69) | 283 (213–416) | 37 (34–40) | 96 (71–121) | 91 (65–136) | 0.95 (0.79–1.32) |
| Acquired VWD | 4 | 2.1 (0.8–6.9) | –/2/2 | 1.47 (1.40–2.24) | 306 (176–356) | 36 (35–57) | 67 (57–95) | 45 (43–48) | 0.68 (0.47–0.77) |
| Normal range | 150–400 | 29–50 | 50–160 | 50–160 | 0.8–4 | ||||
| p Value | 0.23 | – | 0.15 | 0.87 | 0.61 | 0.06 | 0.007 | 0.007 | |