Table 3

Univariate and multivariate hazard ratios for recurrence of MI

UnivariateMultivariate†
Outcome predictorRR95% CIRR95% CI
*p<0.05; **p<0.01; †for 1419 patients.
ACE, angiotensin converting enzyme; CI, confidence interval; RR, relative risk.
Adherence to statins (%)
    0 (n=5163)1.001.00
    <39 (n=67)0.550.25 to 1.220.590.22 to 1.59
    40–79 (n=88)0.38*0.16 to 0.900.510.19 to 1.35
    80–100 (n=272)0.35**0.20 to 0.600.19**0.08 to 0.47
Statin daily dose (high v 10 mg)0.470.18–1.250.420.06 to 3.26
Lipid lowering drug use before MI (yes v no)0.870.45–1.872.58**1.19 to 5.60
Other lipid lowing drugs0.45*0.26 to 0.780.490.22 to 1.14
β Blockers0.67*0.57 to 0.790.65*0.42 to 1.00
Antiplatelet + aspirin0.920.80 to 1.070.930.58 to 1.51
Diuretics0.920.80 to 1.070.58*0.36 to 0.92
ACE inhibitor0.67**0.55 to 0.820.800.49 to 1.31
Other antihypertensive drugs0.630.35 to 1.150.570.20 to 1.63
Nitrates0.910.79 to 1.060.830.51 to 1.36
Calcium channel blocker0.950.82 to 1.111.190.76 to 1.87
Number of types of CV drugs used
    01.001.00
    1–21.251.01 to 1.561.930.90 to 4.15
    3–40.940.77 to 1.151.400.41 to 4.85
    ≥50.63**0.48 to 0.831.890.33 to 10.97
Sex (male v female)0.880.76 to 1.021.130.81 to 1.56
Age (years)
    <501.001.00
    50–591.57*1.06 to 2.341.270.67 to 2.38
    60–691.94*1.34 to 2.822.14*1.17 to 3.92
    70–792.44**1.69 to 3.542.72**1.43 to 5.17
    ≥803.19**2.18 to 4.673.99**1.79 to 8.87
Socioeconomic deprivation
    1–2 (least deprived)1.001.00
    3–41.010.84 to 1.221.010.69 to 1.49
    5–7 (most deprived)1.25*1.03 to 1.521.52*1.04 to 2.21
Baseline cholesterol0.990.90 to 1.101.070.96 to 1.20
Diabetes mellitus2.16**1.69 to 2.762.16**1.38 to 3.37
Year 1994 (after v before)0.800.57 to 1.020.610.30 to 1.22
Other hospitalisation after MI (excluding surgical admission)1.330.93 to 1.881.690.91 to 3.13