anthracycline cardiotoxicity

79 Effective cardioprotection against anthracycline cardiotoxicity in isolated cardiomyocytes and rabbits is based on dexrazoxane interaction with topoisomerase II beta instead of iron chelation by its metabolite ADR-925
Eduard Jirkovsky, Anna Jirkovska, Hana Bavlovic-Piskackova, Veronika Skalicka, Zuzana Pokorna, Galina Karabanovich, Petra Brazdova, Olga Lencova-Popelova, Yvona Mazurova, Michaela Adamcova, Jaroslav Roh, Petra Sterbova-Kovarikova, Tomas Simunek, Martin Sterba

Heart May 2019, 105 (Suppl 6) A67; DOI: 10.1136/heartjnl-2019-BCS.77

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anthracycline cardiotoxicity