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Correspondence
Circadian variations and melatonin in the acute myocardial infarction: still a forgotten extracardiac factor
  1. Alberto Dominguez-Rodriguez1,
  2. Pedro Abreu-Gonzalez2
  1. 1Department of Cardiology, Hospital Universitario de Canarias, Tenerife, Spain
  2. 2Department of Physiology, Universidad de La Laguna, Tenerife, Spain
  1. Correspondence to Dr Alberto Dominguez‐Rodriguez, Hospital Universitario de Canarias, Ofra s.n. La Cuesta, E 38320. Tenerife, Spain; adrvdg{at}hotmail.com

https://doi.org/10.1136/heartjnl-2011-300596

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    To the Editor We read with great interest the article by Suárez-Barrientos et al1 regarding circadian oscillations on infarct size. Although the article is both exhaustive and clinically relevant, we felt that the authors failed in the recognition of the potential value of melatonin in the association between cardiovascular events and circadian variation.

    Synchrony between external and internal circadian rhythms and harmony among molecular fluctuations within cells are essential for normal organ biology. Circadian clocks exist within multiple …

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    Footnotes

    • Linked article 300900.

    • Competing interests None.

    • Provenance and peer review Not commissioned; internally peer reviewed.

    Linked Articles

    • PostScript
      The Author's Reply
      Aida Suárez-Barrientos Borja Ibanez
      Heart 2011; 97 1895-1895 Published Online First: 20 Oct 2011. doi: 10.1136/heartjnl-2011-300900