Summary
The toxicity of silver-coated urinary catheters was assessed using a cell culture technique. The inhibitory effect of catheter extracts on the uptake of 3H-labelled thymidine by mouse fibroblasts was measured. The results show that silver-coating had no toxic effect whereas silvernitrate and silversulphate coating did have a toxic effect.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Akiyama H, Okamoto S (1979) Prophylaxis of indwelling urethral catheter infection: clinical experience with a modified foley catheter and drainage system. J Urol 121:40–46
Graham DT, Mark GE, Pomeroy AR (1983) Cellular toxicity of urinary catheters. Med J Aust 1:456–460
Lundberg T (1986) Prevention of catheter-associated urinarytract infections by use of silver-impregnated catheters. Lancet II:1031
Nacey JN, Delahunt B, Tulloch AGS (1985) The assessment of catheter-induced urethritis using an experimental dog model. J Urol 134:623–627
Nacey JN, Horsfall DJ, Delahunt B, Marshall WR (1986) The assessment of urinary catheter toxicity using cell cultures: validation by comparison with an animal model. J Urol 136:706–709
Ockerblad NF (1949) The silver catheter. J Urol 2:262–265
Ruutu M, Alfthan O, Talja M, Andersson LC (1985) Cytotoxicity of latex urinary catheters. Br J Urol 57:82–86
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Liedberg, H., Lundeberg, T. Assessment of silver-coated urinary catheter toxicity by cell culture. Urol. Res. 17, 359–360 (1989). https://doi.org/10.1007/BF00510526
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00510526