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T 1 Mapping Techniques in Assessment of Ventricular Stiffness

  • Cardiac Nuclear Imaging (A Cuocolo, Section Editor)
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Abstract

Myocardial fibrosis is a fundamental process in the development of heart failure and can be quantified by cardiac magnetic resonance (CMR) imaging with T 1 mapping techniques. By measuring post-contrast myocardial T 1 time and obtaining invasively determined ventricular pressure-volume data, a mechanistic link between diffuse myocardial fibrosis and increased ventricular stiffness has recently been identified. The capacity to non-invasively evaluate diffuse myocardial fibrosis may enhance our understanding of cardiac diseases and facilitate trials of novel therapies.

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Andris H Ellims and Andrew J Taylor declare that they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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  1. Heart Centre, Alfred Hospital, Commercial Road, Melbourne, 3004, Australia

    Andris H. Ellims & Andrew J. Taylor

  2. Baker IDI Heart and Diabetes Research Institute, Melbourne, Australia

    Andris H. Ellims & Andrew J. Taylor

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  1. Andris H. Ellims
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Correspondence to Andrew J. Taylor.

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This article is part of the Topical Collection on Cardiac Nuclear Imaging

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Ellims, A.H., Taylor, A.J. T 1 Mapping Techniques in Assessment of Ventricular Stiffness. Curr Cardiovasc Imaging Rep 8, 1 (2015). https://doi.org/10.1007/s12410-014-9318-5

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