Experimental and laboratory reportThe cyclic changes and structure of the base of the aortic valve☆
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2011, Advanced Drug Delivery ReviewsCitation Excerpt :The natural engineering of the native aortic valve is ideal for its long-term function, which suggests key design criteria for a TEHV. We believe the most important criterion is to precisely mimic the natural anatomic 3D geometry, which is critical for enabling efficient conduit hemodynamics and coronary flow [10,11,401]. A very close second is replicating the regionally heterogeneous tissue compliance of the root and cusp [5,25,78,402].
Reply to the Editor
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This work was supported by NIH Grant HL-17969 (Surgery) and HL-16935 (Anatomy).