Unimproved chest pain in patients with minimal or no coronary disease: A behavioral phenomenon
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2016, International Journal of CardiologyCitation Excerpt :Although a majority of patients was asymptomatic at last follow-up, our study also documents that a relevant proportion of patients has persisting symptoms. It is a well-known phenomenon that patients with small vessel or vasospastic disease have long-lasting symptoms despite treatment [4–21]. Thus, these patients are at risk that their symptoms are sometimes disregarded.
Cardiac Syndrome X: Update
2016, Heart Failure ClinicsCitation Excerpt :Studies have shown that certain behavioral characteristics such as hypochondriasis, anxiety, and panic disorders are common in patients with CSX. Wielgosz and colleagues54 found that among 217 patients, a high hypochondriasis score (assessed by the Minnesota Multiphasic Personality Inventory) was the strongest determinant of continued pain in patients with no coronary artery stenosis. In women experiencing chest pain, a history of anxiety disorders is associated with a lower probability of CAD on angiography.55
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2014, Cardiology ClinicsAnxiety and hypervigilance to cardiopulmonary sensations in non-cardiac chest pain patients with and without psychiatric disorders
2010, Behaviour Research and TherapyCitation Excerpt :In addition, our results showed that the impact of cardiac anxiety on pain was fully mediated by interoceptive fear. Considerable research has shown that the syndrome of NCCP can be persistent in some patients (Potts & Bass, 1993; Wielgosz et al., 1984), and our data suggest that conscious attention to body sensations, particularly those sensations that are perceived as threatening or fearful (i.e., cardiopulmonary sensations), is associated with increased chest pain and impairment. Our findings are consistent with research conducted in the laboratory showing that conscious attention is associated with increased pain (Arntz, Dreessen, & Merckelbach, 1991) – however, the influence of body vigilance on chest pain was partly diminished after accounting for the mediating effect of interoceptive fear.
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2009, Journal of the American College of Cardiology
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This work was supported by Grant HS 03834 from the National Center for Health Services Research and the National Center for Health Care Technology, Hyattsville, Md.; by Research Grants HL-17670 and HL-22740 from the National Heart, Lung and Blood Institute, Bethesda, Md.; by Training Grant LM 07003 and Grant LM 03373 from the National Library of Medicine, Bethesda, Md.; by grants from the Prudential Insurance Company of America, Newark, N.J.; by the Kaiser Family Foundation, Palo Alto, Calif.; by the Andrew W. Mellon Foundation, New York, N.Y.; and by a Canadian Heart Foundation Research Fellowship (Dr. Wielgosz).