Effects of heart rate on phasic coronary blood flow pattern and flow reserve in patients with normal coronary arteries: A study with an intravascular Doppler catheter and spectral analysis
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Influence of Abnormal Glucose Metabolism on Coronary Microvascular Function After a Recent Myocardial Infarction
2009, JACC: Cardiovascular ImagingCitation Excerpt :An increased heart rate demands more oxygen to the myocardium. By autoregulatory mechanisms, the recruitment of the microvasculature increases, resulting in decreased CFR (25). The present study suggests that CFR is reduced in patients with known or newly diagnosed DM, even after adjustment for possible confounders.
Reduced coronary flow reserve in patients with congestive heart failure assessed by transthoracic Doppler echocardiography
2005, Journal of the American Society of EchocardiographyCitation Excerpt :After improvement of CHF, CFR was still far restricted in these patients compared with the normal range reported previously. It has been reported that an increase in HR reduces CFR, because basal CFV is increased without any change in maximal hyperemic CFV.13,14 In this study, although there were no significant differences in blood pressure between both conditions, HR was significantly greater in the condition with CHF compared with that after improvement of CHF.
Phasic coronary blood flow velocity pattern and flow reserve in the atrium: Regulation of left atrial myocardial perfusion
2003, Journal of the American College of CardiologyCitation Excerpt :However, the finding of a disproportionate increase in atrial compared with ventricular MP during stress runs counter to the concept of uniform regulation, rather indicating different mechanisms for atrial and ventricular MP regulation. A reduction of total FVI at maximal hyperemia with increasing HR in the arteries supplying the ventricular myocardium has been reported in two other studies (11,12), consistent with our data. In the present study, CBF responses were assessed using intracoronary Doppler measurement of CBF velocity.
Estimation of coronary flow reserve with the use of dynamic planar and SPECT images of Tc-99m tetrofosmin
2001, Journal of Nuclear CardiologyReperfusion syndrome: Relationship of coronary blood flow reserve to left ventricular function and infarct size
2000, Journal of the American College of CardiologyCitation Excerpt :Finally, pain-to-TIMI 3 time was similar in the two groups. Another limitation is that CVR, the parameter chosen to relate RS to microcirculatory dysfunction, is dependent upon several factors other than microcirculation, such as hemodynamic variables (36) and residual stenosis of the conduit artery (25). However, there was no difference in heart rate, mean arterial blood pressure and residual stenosis among groups, both at initial and predischarge angiography.
Cardiac pacing and coronary hemodynamics
1999, Progress in Cardiovascular Diseases