Clinical studyIdentification of patients with left main and three vessel coronary disease with clinical and exercise test variables
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Cited by (129)
Left Main Coronary Artery Stenosis: State-of-the-Art
2007, Current Problems in CardiologyCitation Excerpt :However there is no single variable that helps either to distinguish LMCA from three-vessel CAD or to predict the presence of LMCA stenosis. The predictive accuracy of TMT findings can be increased to 74% if more than one variable is identified,41 such as development of down-sloping ST depression, ST depression >2 mm, onset of ST changes in stage I, persistence of ST changes beyond 3 minutes, appearance of ST changes in at least three ECG leads, or exertional ST-elevation.42,43 Exercise-induced hypotension occurred in 33% of patients who had at least 75% stenosis of LMCA.44
Anatomic distribution of myocardial ischemia as a determinant of exercise-induced ST-segment depression
2005, American Journal of CardiologyCitation Excerpt :When analysis of covariance was used to adjust for between-group differences in stress severity average and NIS, patients in the contiguous defect group had significantly greater adjusted ST depression than did those in the opposed defect group (2.8 ± 1.15 vs 2.4 ± 1.09 mm, p = 0.001). Because the severity of myocardial ischemia has previously been stratified on the basis of an exercise-induced ST depression >0.2 mV (2.0 mm at standard gain),2,3,18 SPECT findings were compared when patient groups were divided according to this partition. Among patients in the contiguous ischemia group, those who had ST depression >0.2 mV had significantly greater mean SSS (11.5 ± 4.6 vs 8.1 ± 3.7, p <0.01), NIS (5.4 ± 1.8 vs 4.5 ± 1.5, p <0.03), and stress severity average (2.1 ± 0.3 vs 1.8 ± 0.5, p <0.01) than did those whose ST depression was ≤0.2 mV.
Prolonged ST segment depression after stress testing: Does it really identify more severe disease?
2003, International Journal of CardiologyA basic approach to the interpretation of the exercise test
2001, Primary Care - Clinics in Office PracticeCitation Excerpt :There is debate about whether regular ET or ET with radionuclide imaging is the preferred method for predicting severe CAD. When one looks at the amount, pattern, and duration of ST depression, the exercise test has a sensitivity of 50%, a specificity of 92%, and a predictive value of 74%47,30 in predicting severe three vessel of left main disease. Some feel the ET with imaging is superior in identifying severe disease5,32 and the images allow identification of the location of the obstructions.