Relation of coronary artery disease in women <60 years of age to the combined elevation of serum lipoprotein (a) and total cholesterol to high-density cholesterol ratio☆
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Association of menopause and hormone replacement therapy with large artery remodeling
2011, Fertility and SterilityConditional risk factors for atherosclerosis
2005, Mayo Clinic ProceedingsCitation Excerpt :In an elderly cohort, an elevated Lp(a) level was an independent predictor of stroke and death due to vascular disease in men but not women.121 Risk of CHD may be increased synergistically in patients with elevated Lp(a) levels and low levels of HDL cholesterol.122 However, no such interaction was observed in the Framingham Offspring Study.123
Lack of association between lipoprotein(a) and coronary artery calcification in the genetic epidemiology network of arteriopathy (GENOA) study
2004, Mayo Clinic ProceedingsCitation Excerpt :In a study of 788 asymptomatic men aged 35 to 65 years and followed up for 10 years, elevated Lp(a) levels were associated with an increased CHD risk, especially in men with high LDL-C levels, low HDL-C levels, and hypertension.6 In another study, CHD risk was found to be increased synergistically in patients with elevated Lp(a) levels and low levels of HDL-C,25 although such an interaction was not observed in the Framingham Offspring Study.26 Whether Lp(a) is associated with a coronary atherosclerotic burden remains unclear.
Predictors of 14-year changes in the total cholesterol to high-density lipoprotein cholesterol ratio in men
2004, American Heart Journal
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This study was supported in part by the Research Center of the Montreal Heart Institute, Montreal, Quebec, Canada.