Seally symposiumHemodynamic considerations regarding the mechanism and prevention of aortic dissection☆
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Cited by (96)
A Systematic Review and Meta-Analysis of Seasonal and Monthly Variability in the Incidence of Acute Aortic Dissection
2022, Annals of Vascular SurgeryCitation Excerpt :There are many known risk factors for AAD, including arterial hypertension, bicuspid aortic valve, coarctation of the aorta, and Turner syndrome.8 In addition, patients with Marfan's syndrome or other connective tissue diseases are also at high-risk of developing AAD.7,9,10 Chronobiologic research is focused to study the interactions between biological rhythms and the onset of different diseases.11
“Carpe Diem” Professor – In Memoriam of Francis Robicsek (1925-2020)
2020, Annals of Thoracic SurgeryRegional distribution of delamination strength in ascending thoracic aortic aneurysms
2019, Journal of the Mechanical Behavior of Biomedical MaterialsCitation Excerpt :Intramural stresses caused by blood pressure in tandem with factors that may compromise the elasticity and/or strength of the entirety or part of the wall may lead to dilation, and, ultimately, to aortic dissection or rupture. There are two clear mechanisms, which are essential to the natural history of aortic dissection, namely initiation and propagation (Robicsek and Thubrikar, 1994; Humphrey, 2002; Tong et al., 2016). The former involves an intimal-medial tear that occurs when hemodynamic stresses overcome the capacity of inner layers to withstand tensile stress, and the latter involves the catastrophic delamination of wall layers occurring when the bonding forces holding the layers together are overcome.
Effect of Aneurysm and Bicuspid Aortic Valve on Layer-Specific Ascending Aorta Mechanics
2018, Annals of Thoracic SurgeryIdentification of regional/layer differences in failure properties and thickness as important biomechanical factors responsible for the initiation of aortic dissections
2018, Journal of BiomechanicsCitation Excerpt :Rupture of the aortic wall, i.e. loss of integrity across the entire aortic thickness, is the most dramatic end result causing death due to pericardial tamponade or massive hemothorax (Svensson and Crawford, 1992). Identification of the biomechanical factors responsible for the initiation of aortic dissection holds great clinical importance, as has been proposed by Robicsek and Thubrikar (1994; refer also to Thubrikar et al., 1999), since the tear through the inner wall layers occurs when their tensile strength is unable to withstand the hemodynamically-induced stresses. For a review of the equally important problem of the propagation of dissection, see Gasser and Holzapfel (2006), Rajagopal et al. (2007), and Pal et al. (2014).
Acute presentations of valvular heart disease
2018, Cardiac Intensive Care
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Presented at the Cardiovascular Surgery Symposium Honoring Will Camp Sealy, MD, Macon, GA, March 4, 1994.