Brain natriuretic peptide concentrations in patients with aortic stenosis☆,☆☆,★,★★
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Cited by (47)
Natriuretic peptides in aortic stenosis
2012, Revista Portuguesa de CardiologiaCitation Excerpt :The ideal biomarker should be easily and reliably measured, reflect disease severity, increase with disease progression, and discriminate between patients in whom symptoms will or will not develop in the short to medium term. In comparison with controls, AS has been strongly associated with increased NP levels.16,17 In AS, pressure overload induces significant expression of BNP and NT-proBNP.18,19
Usefulness of plasma B-type natriuretic peptide in the assessment of disease severity and prediction of outcome after aortic valve replacement in patients with severe aortic stenosis
2011, Journal of the American Society of EchocardiographyNatriuretic Peptides in Common Valvular Heart Disease
2010, Journal of the American College of CardiologyCitation Excerpt :The ideal biomarker would also allow the identification of a high-risk individual with severe disease before the development of symptoms who could undergo valve surgery without increased perioperative mortality. The presence of AS almost universally has been associated with increased levels of natriuretic peptides when compared with controls (17,38,39), even in asymptomatic mild AS (40,41). This is supported by increased BNP messenger RNA in myocardial samples (42).
Heart failure in patients with aortic stenosis: Clinical and prognostic significance of carbohydrate antigen 125 and brain natriuretic peptide measurement
2008, International Journal of CardiologyCitation Excerpt :Biological markers could complement clinical and echocardiographic evaluation of aortic stenosis patients, providing additional information for choosing the best therapeutic strategies and the optimal timing for valve replacement [18]. Recent studies have demonstrated that natriuretic peptides are correlated in patients with aortic stenosis to transaortic gradient [10], left ventricular end-diastolic pressure [10], left ventricular mass [12] and left ventricular end-systolic wall stress [11]. Gerber et al. demonstrated that increased BNP levels reflect symptom onset in aortic stenosis [14,15].
Recovery of Left Ventricular Systolic Longitudinal Strain After Valve Replacement in Aortic Stenosis and Relation to Natriuretic Peptides
2007, Journal of the American Society of Echocardiography
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From the Departments of aCardiology and bClinical Pharmacology, Ninewells Hospital and Medical School, University of Dundee.
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Reprint requests: Dr. Neeraj Prasad, Department of Cardiology, Stobhill Hospital, Glagow, G21 3UW, United Kingdom.
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Am Heart J 1197;133:477-9.
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